Acyl Bis(monoacylglycero)phosphate, assumed to be a marker for lysosomes, is a major phospholipid of vaccinia virions
Identifieur interne : 003780 ( Main/Exploration ); précédent : 003779; suivant : 003781Acyl Bis(monoacylglycero)phosphate, assumed to be a marker for lysosomes, is a major phospholipid of vaccinia virions
Auteurs : Gerhard Hiller [Allemagne] ; Hansjörg Eibl [Allemagne] ; Klaus Weber [Allemagne]Source :
- Virology [ 0042-6822 ] ; 1981.
English descriptors
- Teeft :
- Acyl, Ammonia, Analog, Bisphosphatidic, Bisphosphatidic acid, Chem, Chromatographic comparison, Debuch, Dipalmitoyl, Eibl, Electron microscopy, Ester, Fatty acid side chains, Fatty acids, Kind gift, Lipid, Liver lysosomes, Lysosome, Major phospholipid, Phospholipase, Phospholipid, Tetrapalmitoyl, Tetrapalmitoyl ester, Total phospholipids, Trace amounts, Vaccinia, Vaccinia virus, Virology, Virus protein.
Abstract
Abstract: A hitherto unknown major phospholipid of purified vaccinia virions harvested from lysed cells was identified as acyl bis(monoacylglycero)phosphate by chromatographic comparison with synthetic bisphosphatidic acid and various analogs. It accounts for 20–30% of the total viral phospholipids. Digestion with pancreatic phospholipase A2 liberates fatty acids and results in bis(monoacylglycero)phosphate, which is thought to represent a phospholipid marker for cellular lysosomes. Possible implications for the intracellular virus dissemination are discussed.
Url:
DOI: 10.1016/0042-6822(81)90204-X
Affiliations:
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It accounts for 20–30% of the total viral phospholipids. Digestion with pancreatic phospholipase A2 liberates fatty acids and results in bis(monoacylglycero)phosphate, which is thought to represent a phospholipid marker for cellular lysosomes. Possible implications for the intracellular virus dissemination are discussed.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Basse-Saxe</li></region><settlement><li>Göttingen</li></settlement></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Hiller, Gerhard" sort="Hiller, Gerhard" uniqKey="Hiller G" first="Gerhard" last="Hiller">Gerhard Hiller</name></region><name sortKey="Eibl, Hansjorg" sort="Eibl, Hansjorg" uniqKey="Eibl H" first="Hansjörg" last="Eibl">Hansjörg Eibl</name><name sortKey="Weber, Klaus" sort="Weber, Klaus" uniqKey="Weber K" first="Klaus" last="Weber">Klaus Weber</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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